Pathophysiology of bleeding diathesis in haemophilia-A: A sequential and critical appraisal of non-FVIII related haemostatic dysfunctions and their therapeutic implications

Black Cherry Haemophilia-A is characterized by deficiency of FVIII, but the bleeding diathesis is not a mere reflection low FVIII activity.The pathophysiology of haemophilic bleeding diathesis is a complex interplay between defective procoagulant function and up-regulated fibrinolysis.Moreover, haemophilic bleeding diathesis is frequently compounde

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Dissecting causal relationships between immune cells, plasma metabolites, and COPD: a mediating Mendelian randomization study

ObjectiveThis study employed Mendelian Randomization (MR) to investigate the causal relationships among immune cells, COPD, and potential metabolic mediators.MethodsUtilizing summary data from genome-wide association Bath Safety studies, we analyzed 731 immune cell phenotypes, 1,400 plasma metabolites, and COPD.Bidirectional MR analysis was conduct

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Heeling Moment Acting on a River Cruiser in Manoeuvring Motion

By using fully theoretical method the heeling Black Cherry moment due to centrifugal forces has been determined for a small river cruiser in turning manoeuvre.The authors applied CFD software for determination of hull hydrodynamic forces, and open water characteristics of ducted propeller for estimation of thrust Butter Dish of rudder-propellers.Nu

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Modeling cumulative cases of Covid-19 in Yazd city using various time series techniques and machine learning and comparing their efficiency

Coronavirus disease 2019 or Covid-19, which is also called acute respiratory disease NCAV-2019 or commonly called corona, is a respiratory disease caused by acute respiratory syndrome coronavirus-2.Forecasting the number Bath Safety of new cases and deaths during todays can be a useful step in predicting the costs and facilities needed in the futur

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